Thrombosis and Endothelial Injury

did not meet the criteria: this point was detailed in the fifth paragraph of the discussion. According to our criteria it is not true that after exclusion of 6 patients with associated infarcts, 7 of the 10 remaining subjects fulfilled criteria for small-vessel occlusion: none of these 10 did. Only 1 patient (of 16) met criteria for small vessel-occlusion in our study, this patient had an associated ipsilateral thalamic infarct (see table). Dr Bruno agrees with the general conclusion of our study: the rule "anterior choroidal artery territory infarct=small-vessel occlusion" is not true for all patients, and patients with such infarcts should be systematically evaluated for possible large-vessel disease and cardioembolism. This remains the finding most important to determining the best therapeutic strategy for the secondary prevention of stroke in these patients.